DORA-12 | Orexin receptor antagonist | Probechem Biochemicals

Chemical Structure : DORA-12

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货号: PC-22236Not For Human Use, Lab Use Only.

DORA-12 (Dual orexin receptor antagonist 12) is a potent, dual orexin receptor (OX1R/OX2R) antagonist with Ki of 1.8/0.2 nM, respectively.

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DORA-12 (Dual orexin receptor antagonist 12) is a potent, dual orexin receptor (OX1R/OX2R) antagonist with Ki of 1.8/0.2 nM, respectively.

分子量	431.48
分子式	C23H22FN7O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-(2-(2H-1,2,3-triazol-2-yl)phenyl)(4-(6-fluoroquinazolin-2-yl)-7-methyl-1,4-diazepan-1-yl)methanone

1. Ramirez AD, et al. Front Neurosci. 2013 Dec 24;7:254.

2. Ehlers CL, et al. Psychopharmacology (Berl). 2020 Oct;237(10):2917-2927.

3. Cady RJ, et al. Neuroscience. 2014 Jun 6;269:79-92.