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DNS-pE2

Chemical Structure : DNS-pE2

CAS No.:

DNS-pE2

货号: PC-62582Not For Human Use, Lab Use Only.

DNS-pE2 is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DNS-pE2 is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.
    DNS-pE2 is highly fluorescent only upon irreversible covalent modification of PHGDH with an inhibitory property (in vitro Ki=7.4 uM).

    物理化学性质&存储条件

    分子量 285.361
    分子式 C16H15NO2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-methyl-N-(prop-2-yn-1-yl)-6-(vinylsulfonyl)naphthalen-2-amine

    参考文献

    1. Pan S, et al. Angew Chem Int Ed Engl. 2018 Jan 8;57(2):579-583.

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