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首页-小分子抑制剂&激动剂-Others-Fluorescent Dye-DNS-pE
DNS-pE

Chemical Structure : DNS-pE

CAS No.:

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DNS-pE (PHGDH Fluorescent Probe DNS-pE)

货号: PC-62599Not For Human Use, Lab Use Only.

DNS-pE (PHGDH Fluorescent Probe DNS-pE) is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DNS-pE (PHGDH Fluorescent Probe DNS-pE) is the first small molecule that can selectively label endogenous 3-phosphoglycerate dehydrogenase (PHGDH) from various mammalian cells.
    DNS-pE is highly fluorescent only upon irreversible covalent modification of PHGDH with an inhibitory property (in vitro Ki=7.4 uM).

    物理化学性质&存储条件

    分子量 261.339
    分子式 C14H15NO2S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N,N-dimethyl-6-(vinylsulfonyl)naphthalen-2-amine

    参考文献

    1. Pan S, et al. Angew Chem Int Ed Engl. 2018 Jan 8;57(2):579-583.

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