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首页-新冠病毒相关-SARS-CoV-2 Inhibitors-DNDI-6510
DNDI-6510

Chemical Structure : DNDI-6510

CAS No.: 2765434-56-6

DNDI-6510 ((S)-x38)

货号: PC-25261Not For Human Use, Lab Use Only.

DNDI-6510 ((S)-x38) is a non-covalent, potent SARS-CoV-2, isoquinoline-based MPro inhibitor with IC50 of 40 nM, SARS-CoV-2 EC50 of 0.17 uM (A549 cells).

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DNDI-6510 ((S)-x38) is a non-covalent, potent SARS-CoV-2, isoquinoline-based MPro inhibitor with IC50 of 40 nM, SARS-CoV-2 EC50 of 0.17 uM (A549 cells).

物理化学性质&存储条件

分子量 474.95
分子式 C26H23ClN4O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-1-(6-chloro-1'-(isoquinolin-4-yl)-1,2'-dioxo-1H-spiro[isoquinoline-4,3'-pyrrolidin]-2(3H)-yl)-N-methylcyclopropane-1-carboxamide

参考文献

1. Griffen EJ, et al. bioRxiv [Preprint]. 2025 Jun 17:2025.06.16.660018.

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