DNA-PK inhibitor 78

Chemical Structure : DNA-PK inhibitor 78

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货号: PC-22698Not For Human Use, Lab Use Only.

DNA-PK inhibitor 78 is a potent, selective DNA-PK inhibitor with IC50 of 7.95 nM, >200-fold selective over PI3Kα and >800-fold over other PI3Ks and mTOR.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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DNA-PK inhibitor 78 is a potent, selective DNA-PK inhibitor with IC50 of 7.95 nM, >200-fold selective over PI3Kα and >800-fold over other PI3Ks and mTOR.

物理化学性质&存储条件

分子量	368.44
分子式	C20H24N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	6-((4-Methoxy-2-methylphenyl)amino)-3-methyl-1-(tetrahydro-2H-pyran-4-yl)-1,3-dihydro-2H-imidazo[4,5-c]pyridin-2-one

参考文献

1. Hong CR, et al. J Med Chem. 2024 Jul 15. doi: 10.1021/acs.jmedchem.4c01120.