DMT1 inhibitor 6b |CAS:1062598-09-7 Probechem Biochemicals

Chemical Structure : DMT1 inhibitor 6b

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DMT1 inhibitor 6b (XEN602 analog 2)

货号: PC-38324Not For Human Use, Lab Use Only.

DMT1 inhibitor 6b is a potent inhibitor of divalent metal transporter 1 (DMT1) with IC50 of 80 nM in calcein fluorescence assay.

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生物&药学活性

DMT1 inhibitor 6b is a potent inhibitor of divalent metal transporter 1 (DMT1) with IC50 of 80 nM in calcein fluorescence assay.
DMT1 inhibitor 6b demonstrated significant iron absorption inhibition in vivo with both 25 and 50 mg/kg doses in an acute rat model of iron hyperabsorption.

物理化学性质&存储条件

分子量	380.518
分子式	C16H17FN4S3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

参考文献

1. Zaihui Zhang, et al. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5108-13.

DMT1 inhibitor 6b (XEN602 analog 2)

生物&药学活性

物理化学性质&存储条件

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DMT1 inhibitor 6b (XEN602 analog 2)

生物&药学活性

物理化学性质&存储条件

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