Chemical Structure : DMJ-I-228
货号: PC-70320Not For Human Use, Lab Use Only.
DMJ-I-228 is a small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
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DMJ-I-228 is a small molecule CD4-mimetic that binds gp120 and blocks CD4 binding, inhibits HIV-1 entry with IC50 of 86.9 uM.
分子量 | 435.84 | |
分子式 | C19H19ClFN5O4 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Madani N, et al. Structure. 2008 Nov 12; 16(11):1689-701.
2. Richard J, et al. Proc Natl Acad Sci U S A. 2015 May 19;112(20):E2687-94.
3. LaLonde JM, et al. J Med Chem. 2012 May 10;55(9):4382-96.
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