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DMGA

Chemical Structure : DMGA

CAS No.: 17339-60-5

DMGA

货号: PC-49528Not For Human Use, Lab Use Only.

DMGA is an allosteric and covalent inhibitor of SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro) with IC50 of 9.4 uM, covalently binds with C270 of the SARS-CoV-2 PLpro.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

DMGA is an allosteric and covalent inhibitor of SARS-CoV-2 papain-like protease (SARS-CoV-2 PLpro) with IC50 of 9.4 uM, covalently binds with C270 of the SARS-CoV-2 PLpro.

物理化学性质&存储条件

分子量 281.30
分子式 C8H22Cl2N2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Ethanamine, 2,2′-dithiobis[N,N-dimethyl-, hydrochloride (1:2)

参考文献

1. Hangchen Hu, et al. Angew Chem Int Ed Engl. 2022 Oct 29. doi: 10.1002/anie.202212378.

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