Chemical Structure : DLin-MC3-DMA
CAS No.: 1224606-06-7
货号: PC-73149Not For Human Use, Lab Use Only.
DLin-MC3-DMA is an ionizable amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles.
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---|---|---|---|
5 mg | ¥1280 | In stock | |
10 mg | ¥1880 | In stock | |
25 mg | ¥2980 | In stock | |
50 mg | ¥4780 | In stock | |
100 mg | ¥7580 | In stock | |
250 mg | Get quote |
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DLin-MC3-DMA is an ionizable amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles.
Administration of Factor VII siRNA in DLin-MC3-DMA-containing lipid nanoparticles reduces plasma Factor VII protein levels in mice.
Formulations containing DLin-MC3-DMA have been used in the development of lipid nanoparticles for siRNA delivery in patients with hereditary transthyretin-mediated amyloidosis.
分子量 | 642.1 | |
分子式 | C43H79NO2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
100 mM in Ethanol (64.2 mg/mL) |
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Chemical Name/SMILES |
(6Z,9Z,28Z,31Z)-Heptatriaconta-6,9,28,31-tetraen-19-yl 4-(dimethylamino)butanoate |
1. Kulkarni JA, et al. Nanomedicine. 2017 May;13(4):1377-1387.
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