DLK-LZK inhibitor 64

Chemical Structure : DLK-LZK inhibitor 64

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货号: PC-49571Not For Human Use, Lab Use Only.

DLK-LZK inhibitor 64 (example 64) is a potent, selective dual leucine zipper kinase (DLK, MAP3K12) and leucine zipper-bearing kinase (LZK) inhibitor with IC50 of 2 nM and 10 nM, respectively.

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生物&药学活性

DLK-LZK inhibitor 64 (example 64) is a potent, selective dual leucine zipper kinase (DLK, MAP3K12) and leucine zipper-bearing kinase (LZK) inhibitor with IC50 of 2 nM and 10 nM, respectively.

物理化学性质&存储条件

分子量	451.494
分子式	C22H28F3N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(6-amino-5-(trifluoromethyl)pyridin-3-yl)-1-(3-morpholinobicyclo[1.1.1]pentan-1-yl)-1H-imidazol-2-yl)-2-methylpropan-1-ol

参考文献

1. U.S. Patent 20,180,186,781 A1, Exmaple 64.