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DKFZ-633

Chemical Structure : DKFZ-633

CAS No.: 2244425-14-5

DKFZ-633 (DKFZ633;DKFZ 633)

货号: PC-35660Not For Human Use, Lab Use Only.

DKFZ-633 (DKFZ633) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.25 uM, demonstrates good selectivity for KLK6 compared to other KLKs.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DKFZ-633 (DKFZ633) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.25 uM, demonstrates good selectivity for KLK6 compared to other KLKs.
    DKFZ-633 is a useful chemical probe to pull down active endogenous KLK6.

    物理化学性质&存储条件

    分子量 440.503
    分子式 C26H24N4O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-((3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)amino)-2-oxoethyl 2-(5-ethynyl-2-methyl-1H-indol-3-yl)acetate

    参考文献

    1. De Vita E, et al. J Med Chem. 2018 Sep 28. doi: 10.1021/acs.jmedchem.8b01106.

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