DKFZ-251 |CAS:2222059-70-1 Probechem Biochemicals

Chemical Structure : DKFZ-251

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DKFZ-251 (DKFZ251;DKFZ 251)

货号: PC-35697Not For Human Use, Lab Use Only.

DKFZ-251 (DKFZ251) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.13 uM, demonstrates good selectivity for KLK6 compared to other KLKs.

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生物&药学活性

DKFZ-251 (DKFZ251) is a selective inhibitor of Kallikrein-related peptidase 6 (KLK6) with IC50 of 0.13 uM, demonstrates good selectivity for KLK6 compared to other KLKs.
DKFZ-633 exhibits on-target activity in a cellular assay.

物理化学性质&存储条件

分子量	416.481
分子式	C24H24N4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)amino)-2-oxoethyl 2-(2-methyl-1H-indol-3-yl)acetate

参考文献

1. De Vita E, et al. J Med Chem. 2018 Sep 28. doi: 10.1021/acs.jmedchem.8b01106.

DKFZ-251 (DKFZ251;DKFZ 251)

生物&药学活性

物理化学性质&存储条件

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DKFZ-251 (DKFZ251;DKFZ 251)

生物&药学活性

物理化学性质&存储条件

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