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首页-小分子抑制剂&激动剂-Others-Other Targets-DHAB
DHAB

Chemical Structure : DHAB

CAS No.: 51437-66-2

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DHAB (4,4'-Dihydroxyazobenzene)

货号: PC-20400Not For Human Use, Lab Use Only.

DHAB is a potent, specific small molecule inhibitor of kidney ADPR-cyclase with IC50 of 2.5 nM, does not inhibit CD38, spleen, heart or brain ADPR-cyclase activity in vitro.

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100 mg ￥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

DHAB is a potent, specific small molecule inhibitor of kidney ADPR-cyclase with IC50 of 2.5 nM, does not inhibit CD38, spleen, heart or brain ADPR-cyclase activity in vitro.
DHAB inhibits cADPR production stimulated by CaSR in MMC at <5 nM.

物理化学性质&存储条件

分子量 214.22
分子式 C12H10N2O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4,4'-(diazene-1,2-diyl)diphenol

参考文献

1. Tae-Sik Nam, et al. Exp Mol Med. 2006 Dec 31;38(6):718-26.

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