Chemical Structure : DDC4002
货号: PC-21851Not For Human Use, Lab Use Only.
DDC4002 is a potent, selective and allosteric EGFR inhibitor, shows selectivity against L858R/T790M/C797S EGFR mutants with IC50 of 39-50 nM, does not inhibit WT EGFR.
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DDC4002 is a potent, selective and allosteric EGFR inhibitor, shows selectivity against L858R/T790M/C797S EGFR mutants with IC50 of 39-50 nM, does not inhibit WT EGFR.
分子量 | 318.35 | |
分子式 | C20H15FN2O | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Maity S, et al. Pharmacol Rep. 2020 Aug;72(4):799-813.
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