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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Glycine Transporter (GlyT)-DCCCyB
DCCCyB

Chemical Structure : DCCCyB

CAS No.: 1236046-15-3

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DCCCyB (GlyT1 inhibitor)

货号: PC-61457Not For Human Use, Lab Use Only.

DCCCyB is a potent, selective, orally available GlyT1 inhibitor with IC50 of 29 nM, demonstrates excellent in vivo occupancy of GlyT1 transporters in vivo.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DCCCyB is a potent, selective, orally available GlyT1 inhibitor with IC50 of 29 nM, demonstrates excellent in vivo occupancy of GlyT1 transporters in vivo.

    物理化学性质&存储条件

    分子量 458.438
    分子式 C22H29Cl2NO3S
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2,4-dichloro-N-(((1s,4s)-1-(cyclopropylmethyl)-4-((cyclopropylmethyl)sulfonyl)cyclohexyl)methyl)benzamide

    参考文献

    1. Blackaby WP, et al. ACS Med Chem Lett. 2010 Jun 25;1(7):350-4.

    2. Yamamoto S, et al. Chem Pharm Bull (Tokyo). 2016;64(11):1630-1640.

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