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首页-小分子抑制剂&激动剂-Autophagy-ULK-DCC-3116
DCC-3116

Chemical Structure : DCC-3116

CAS No.: 2543673-19-2

DCC-3116 (DCC3116)

货号: PC-72327Not For Human Use, Lab Use Only.

DCC-3116 (DCC3116) is a first-in-class, selective inhibitor of ULK1/2 kinases (IC50=4.7/35 nM) and autophagy.

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5 mg ¥780 In stock
10 mg ¥1180 In stock
25 mg ¥1980 In stock
50 mg ¥3280 In stock
100 mg Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

DCC-3116 (DCC3116) is a first-in-class, selective inhibitor of ULK1/2 kinases (IC50=4.7/35 nM) and autophagy.

物理化学性质&存储条件

分子量 535.62
分子式 C26H36F3N7O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 Month
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(3-((2-((2-ethyl-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)propyl)-1,4-oxazepan-5-one

参考文献

1. Ghazi PC, et al. bioRxiv [Preprint]. 2024 Feb 8:2024.02.06.579200.
2. Patent WO2024050351 A1.

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