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首页-抗体药物偶连体和PROTACs-ADCs Linker/Click Chemistry-DBCO-Amine
DBCO-Amine

Chemical Structure : DBCO-Amine

CAS No.: 1255942-06-3

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DBCO-Amine (DBCO amine)

货号: PC-70007Not For Human Use, Lab Use Only.

A simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

A simple DBCO-containing building block used to derivatize carboxyl groups in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) with DBCO moiety through a stable amide bond; A click chemistry tool used to conjugate DBCO-PEG4-MMAF to the introduced non-natural amino acid pAMF using a noncleavable linker.

物理化学性质&存储条件

分子量 276.339
分子式 C18H16N2O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3-Amino-1-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-1-propanone

参考文献

1. Currier NV, et al. Mol Cancer Ther. 2016 Jun;15(6):1291-300.

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