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首页-小分子抑制剂&激动剂-Epigenetics-HDAC-DAC-001
DAC-001

Chemical Structure : DAC-001

CAS No.: 701248-16-0

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DAC-001 (Deacetylase-activating compound)

货号: PC-25166Not For Human Use, Lab Use Only.

DAC-001 is a small molecule, cell-active activator of HDAC1, exhibits dose-dependent activation of HDAC1 in vitro in a microfluidics-based assay at 5-10 uM, displayes significant protection against DNA breaks.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DAC-001 is a small molecule, cell-active activator of HDAC1, exhibits dose-dependent activation of HDAC1 in vitro in a microfluidics-based assay at 5-10 uM, displayes significant protection against DNA breaks.

物理化学性质&存储条件

分子量 366.44
分子式 C20H18N2O3S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-((4-(5-(hydroxymethyl)furan-2-yl)phenyl)carbamothioyl)-4-methylbenzamide

参考文献

1. L.-H. Tsai, S.J. et al. Activators of Class i Histone Deacetlyases (Hdacs) and Uses Thereof (2013). WO 2013/016193 A2.

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