D77 |CAS:497836-10-9 Probechem Biochemicals

Chemical Structure : D77

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D77 (D-77)

货号: PC-45509Not For Human Use, Lab Use Only.

D77 is a potent inhibitor of HIV-1 integrase-LEDGF/p75 interaction binds to IN and IN(T125A) with Kd of 5.81 and 15.2 uM.

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生物&药学活性

D77 is a potent inhibitor of HIV-1 integrase-LEDGF/p75 interaction binds to IN and IN(T125A) with Kd of 5.81 and 15.2 uM.
D77 affects the HIV-1 IN nuclear distribution thus exhibiting antiretroviral activity.

物理化学性质&存储条件

分子量	596.4458
分子式	C28H22BrNO7S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzoic acid, 4-[[5-bromo-4-[[2,4-dioxo-3-(2-oxo-2-phenylethyl)-5-thiazolidinylidene]methyl]-2-ethoxyphenoxy]methyl]-

参考文献

1. Du L, et al. Biochem Biophys Res Commun. 2008 Oct 10;375(1):139-44.

2. Li P, et al. J Biomol Struct Dyn. 2011 Oct;29(2):311-23.

D77 (D-77)

生物&药学活性

物理化学性质&存储条件

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D77 (D-77)

生物&药学活性

物理化学性质&存储条件

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