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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Phospholipase-D609
D609

Chemical Structure : D609

CAS No.: 83373-60-8

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D609 (D-609)

货号: PC-45953Not For Human Use, Lab Use Only.

D609 is a competitive inhibitor of PC-PLC with Ki of 6.4 uM, also is a small molecule of sphingomyelin synthase (SMS1 and SMS2).

规格 价格 库存 数量
5 mg ￥480 In stock
10 mg ￥780 In stock
25 mg ￥1280 In stock
50 mg ￥1980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

D609 is a competitive inhibitor of PC-PLC with Ki of 6.4 uM, also is a small molecule of sphingomyelin synthase (SMS1 and SMS2).
D609 does not affect bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D; has antioxidant, antiviral, and anti-tumor activities.
D609 also shows anti-inflammatory actions, blocking the induction of nitric oxide synthase by LPS in phagocytes (IC50=20 ug/ml).

物理化学性质&存储条件

分子量 266.4645
分子式 C11H15KOS2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Carbonodithioic acid, O-(octahydro-4,7-methano-1H-inden-5-yl) ester, potassium salt (1:1)

参考文献

1. Amtmann E. Drugs Exp Clin Res. 1996;22(6):287-94.

2. Adibhatla RM, et al. Neurochem Res. 2012 Apr;37(4):671-9.

3. Tschaikowsky K, et al. Br J Pharmacol. 1994 Nov;113(3):664-8.

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