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首页-小分子抑制剂&激动剂-GPCR-Dopamine Receptor-D5R agonist 5j
D5R agonist 5j

Chemical Structure : D5R agonist 5j

CAS No.:

D5R agonist 5j

货号: PC-23109Not For Human Use, Lab Use Only.

D5R agonist 5j is a selective dopamine D5 receptor (D5R) partial agonist with EC50 of 269.7 nM, not active at the other four dopamine receptors.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

D5R agonist 5j is a selective dopamine D5 receptor (D5R) partial agonist with EC50 of 269.7 nM, not active at the other four dopamine receptors.
D5R agonist 5j readily crosses the BBB and enhances the cognition in the scopolamine-induced amnesia model.

物理化学性质&存储条件

分子量 463.28
分子式 C19H18IN3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(4-iodophenyl)-6-(2,4,5-trimethoxyphenyl)pyrimidin-2-amine

参考文献

1. Sakesh Kumar, et al. Bioorg Chem. 2024 Sep 7:153:107809.

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