D159153 |CAS 2734371-28-7 Probechem Biochemicals

Chemical Structure : D159153

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货号: PC-35906Not For Human Use, Lab Use Only.

D159153 (D-159153) is a novel potent, allosteric inhibitor of PDE4 with cellular IC50 of 28.5 and 6.6 nM for PDE4B1 and PDE4D3, respectively.

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D159153 (D-159153) is a novel potent, allosteric inhibitor of PDE4 with cellular IC50 of 28.5 and 6.6 nM for PDE4B1 and PDE4D3, respectively.

分子量	397.45
分子式	C22H24FN3O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(4-ethyl-2-fluoro-3-((2E,4E)-5-nitrohexa-2,4-dien-3-yl)benzyl)phenyl)urea

1. Wunder F, et al. Mol Pharm. 2013 Oct 7;10(10):3697-705.

2. Zhang C, et al. Neuropsychopharmacology. 2018 Oct;43(11):2299-2309.