D13-9001 | MexAB-OprM inhibitor | Probechem Biochemicals

Chemical Structure : D13-9001

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D13-9001 (D 13-9001)

货号: PC-35872Not For Human Use, Lab Use Only.

D13-9001 (D 13-9001) is a small molecule, MexAB-OprM specific efflux pump inhibitor with good potency in vitro (MPC 2 ug/mL) and displays excellent activity in vivo in a rat pneumonia model of P. aeruginosa.

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生物&药学活性

物理化学性质&存储条件

分子量	1386.604
分子式	C63H81N22O11S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Ethanaminium, N-(carboxymethyl)-2-[[[[(3R)-1-[8-[[[4-(1,1-dimethylethyl)-2-thiazolyl]amino]carbonyl]-4-oxo-3-[(1E)-2-(2H-tetrazol-5-yl)ethenyl]-4H-pyrido[1,2-a]pyrimidin-2-yl]-3-piperidinyl]oxy]carbonyl]amino]-N,N-dimethyl-, inner salt

参考文献

1. Ranjitkar S, et al. Antimicrob Agents Chemother. 2018 Nov 12. pii: AAC.01718-18. doi: 10.1128/AAC.01718-18.

2. Yoshida K, et al. Bioorg Med Chem. 2007 Nov 15;15(22):7087-97.

D13-9001 (D 13-9001)

生物&药学活性

物理化学性质&存储条件

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D13-9001 (D 13-9001)

生物&药学活性

物理化学性质&存储条件

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