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D-Fagomine

Chemical Structure : D-Fagomine

CAS No.: 53185-12-9

D-Fagomine (Fagomine)

货号: PC-43315Not For Human Use, Lab Use Only.

D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

D-Fagomine (Fagomine) is a a mild glycosidase inhibitor, inhibits Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast) with Ki of 4.8 uM, 39 uM, and 70 uM, respectively.
D-Fagomine counteracts the short-term effects of a high-energy-dense diet on body weight, fasting blood glucose levels and the proportion of gut Enterobacteriales, reduces the amount of Enterobacteriales excreted by rats fed HFHS.

物理化学性质&存储条件

分子量 147.1723
分子式 C6H13NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

H2O: ≥ 36 mg/mL

Chemical Name/SMILES

3,4-Piperidinediol, 2-(hydroxymethyl)-, (2R,3R,4R)-

参考文献

1. Molyneux RJ, et al. J Nat Prod. 1993 Aug;56(8):1356-64.

2. Molinar-Toribio E, et al. Food Funct. 2015 Aug;6(8):2614-9.

3. Mena-Barragán T, et al. Eur J Med Chem. 2016 Oct 4;121:880-891.

4. Ramos-Romero S, et al. Obesity (Silver Spring). 2014 Apr;22(4):976-9.

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