D-Cl-amidine hydrochloride

Chemical Structure : D-Cl-amidine hydrochloride

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货号: PC-27308Not For Human Use, Lab Use Only.

D-Cl-amidine hydrochloride is a potent and highly selective PAD1 inhibitor with kinact/KI of 1220 M-1 min-1, displays 50-, 204- and 10-fold selectivity over PAD2, PAD3 and PAD4 respectively.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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生物&药学活性

D-Cl-amidine hydrochloride is a potent and highly selective PAD1 inhibitor with kinact/KI of 1220 M-1 min-1, displays 50-, 204- and 10-fold selectivity over PAD2, PAD3 and PAD4 respectively.

物理化学性质&存储条件

分子量	347.24
分子式	C14H20Cl2N4O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(R)-N-(1-amino-5-(2-chloroacetimidamido)-1-oxopentan-2-yl)benzamide hydrochloride

参考文献

1. Bicker KL, et al. ACS Med. Chem. Lett 3 (12) (2012) 1081–1085.