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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-Nur77 (NR4A1)-Cytosporone B
Cytosporone B

Chemical Structure : Cytosporone B

CAS No.: 321661-62-5

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Cytosporone B (Csn-B, Dothiorelone G)

货号: PC-23124Not For Human Use, Lab Use Only.

Cytosporone B (Csn-B, Dothiorelone G) is a specific naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with EC50 of 0.278 nM, targets the ligand binding domain of Nur77.

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25 mg ￥2680 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cytosporone B (Csn-B, Dothiorelone G) is a specific naturally occurring nuclear orphan receptor Nur77 (NR4A1) agonist with EC50 of 0.278 nM, targets the ligand binding domain of Nur77.

物理化学性质&存储条件

分子量 322.40
分子式 C18H26O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ethyl 2-(3,5-dihydroxy-2-octanoylphenyl)acetate

参考文献

1. Zhan Y, et al. Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat Chem Biol. 2008 Sep;4(9):548-56.

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