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首页-小分子抑制剂&激动剂-GPCR-5-HT Receptor-Cyproheptadine
Cyproheptadine

Chemical Structure : Cyproheptadine

CAS No.: 969-33-5

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Cyproheptadine

货号: PC-26505Not For Human Use, Lab Use Only.

Cyproheptadine hydrochloride is a potent and orally active 5-HT2A receptor antagonist and histamine H1 receptor (HRH1) inverse agonist, promotes FOXO3 nuclear translocation and increases FOXO target genes while suppressing inflammation.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cyproheptadine hydrochloride is a potent and orally active 5-HT2A receptor antagonist and histamine H1 receptor (HRH1) inverse agonist, promotes FOXO3 nuclear translocation and increases FOXO target genes while suppressing inflammation.

物理化学性质&存储条件

分子量 323.86
分子式 C21H22ClN
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride

参考文献

1. Kurakazu I, et al. J Clin Invest. 2025 Aug 28;135(21):e183588.

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