Cyclocreatine Phosphate |CAS:18838-38-5 Probechem Biochemicals

Chemical Structure : Cyclocreatine Phosphate

CAS No.: 18838-38-5

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Cyclocreatine Phosphate (AM 285)

货号: PC-61918Not For Human Use, Lab Use Only.

Cyclocreatine Phosphate (AM 285) is an analog of the creatine kinase CKMT1 substrate creatine and inhibitor of the creatine biosynthesis pathway.

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100 mg	￥580	In stock
250 mg	￥980	In stock
1 g		Get quote

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生物&药学活性

Cyclocreatine Phosphate (AM 285) is an analog of the creatine kinase CKMT1 substrate creatine and inhibitor of the creatine biosynthesis pathway.
Cyclocreatine Phosphate (AM 285) decreases intracellular ATP level, suppresses arginine-creatine metabolism, selectively decreases the viability, promotes cell cycle arrest and apoptosis of human EVI1-positive AML cells.
Cyclocreatine Phosphate (AM 285) prolongs survival in human orthotopic and mouse primary AML models.

物理化学性质&存储条件

分子量	287.3
分子式	C4H8N3O5P • 2K
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[imino(phosphonoamino)methyl]-N-methyl-glycine, dipotassium salt

参考文献

1. Woznicki DT, et al. J Neurochem. 1988 May;50(5):1640-7.

2. Turner DM, et al. J Biol Chem. 1987 May 15;262(14):6605-9.

3. Griffiths GR, et al. J Biol Chem. 1976 Apr 10;251(7):2049-54.

Cyclocreatine Phosphate (AM 285)

生物&药学活性

物理化学性质&存储条件

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Cyclocreatine Phosphate (AM 285)

生物&药学活性

物理化学性质&存储条件

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