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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-Telomerase-Cycloastragenol
Cycloastragenol

Chemical Structure : Cycloastragenol

CAS No.: 84605-18-5

Cycloastragenol (Cyclogalagenin;Cyclogalegenin;Cyclogalegigenin;GRN-510;TAT-2)

货号: PC-47447Not For Human Use, Lab Use Only.

A natural tetracyclic triterpenoid that is a potent telomerase activator.

规格 价格 库存 数量
25 mg ¥780 In stock
50 mg ¥1280 In stock
100 mg ¥1980 In stock
200 mg Get quote
1 g Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cycloastragenol (Cyclogalagenin, GRN-510) is a natural tetracyclic triterpenoid that is a potent telomerase activator.
Cycloastragenol modestly retards telomere shortening, increases proliferative potential, and, importantly, enhances cytokine/chemokine production and antiviral activity.
Cycloastragenol suppresses lung damage in a murine model of idiopathic pulmonary fibrosis.

物理化学性质&存储条件

分子量 490.72
分子式 C30H50O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2aR,3R,4S,5aS,5bS,7S,7aR,9S,11aR,12aS)-3-((2R,5S)-5-(2-Hydroxypropan-2-yl)-2-methyltetrahydrofuran-2-yl)-2a,5a,8,8-tetramethylhexadecahydrocyclopenta[a]cyclopropa[e]phenanthrene-4,7,9-triol

参考文献

1. Fauce SR, et al. J Immunol. 2008 Nov 15;181(10):7400-6.

2. Yung LY, et al. Planta Med. 2012 Jan;78(2):115-21.

3. Le Saux CJ, et al. PLoS One. 2013;8(3):e58423.

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