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首页-小分子抑制剂&激动剂-Others-SMN2 Modulator-Cuspin-1
Cuspin-1

Chemical Structure : Cuspin-1

CAS No.: 337932-29-3

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Cuspin-1 (Cuspin1)

货号: PC-62370Not For Human Use, Lab Use Only.

Cuspin-1 is a small molecule upregulator of SMN (Survival of Motor Neuron protein) with EC50 of 18 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Cuspin-1 is a small molecule upregulator of SMN (Survival of Motor Neuron protein) with EC50 of 18 uM.
    Cuspin-1 increases Ras signaling and upregulates SMN protein abundance via an increase in translation rate.

    物理化学性质&存储条件

    分子量 276.13
    分子式 C13H10BrNO
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (5-bromo-3-pyridinyl)(4-methylphenyl)-methanone

    参考文献

    1. Letso RR, et al. ACS Chem Biol. 2013 May 17;8(5):914-22.

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