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首页-小分子抑制剂&激动剂-Immunology/Inflammation-STING-Cridanimod sodium
Cridanimod sodium

Chemical Structure : Cridanimod sodium

CAS No.: 58880-43-6

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Cridanimod sodium (XBIO-101, XBIO101)

货号: PC-60187Not For Human Use, Lab Use Only.

Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
    Cridanimod sodium (XBIO-101) displays extraordinary activity in phosphorylating IRF3 in the murine system.
    Cridanimod sodium (XBIO-101) also increases progesterone receptor (PrR) expression in endometrial tissue.

    物理化学性质&存储条件

    分子量 276.247
    分子式 C15H11NNaO3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(9-oxoacridin-10(9H)-yl)acetic acid, sodium salt

    参考文献

    1. Cavlar T, et al. EMBO J. 2013 May 15;32(10):1440-50.

    2. Zhang H, et al. Sci Rep. 2015 Dec 16;5:18035.

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