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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-CFTR-Corr4A
Corr4A

Chemical Structure : Corr4A

CAS No.: 421580-53-2

Corr4A (Corr 4A)

货号: PC-60652Not For Human Use, Lab Use Only.

Corr4A is a small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.

规格 价格 库存 数量
25 mg Get quote
100 mg Get quote
250 mg Get quote
1 g Get quote

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Corr4A is a small molecule corrector of ΔF508-CFTR with IC50 of 6.0 uM.

物理化学性质&存储条件

分子量 456.963
分子式 C21H17ClN4O2S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-[2-(5-chloro-2-methoxy-phenylamino)-4'-methyl-[4,5']bithiazolyl-2'-yl]-benzamide

参考文献

1. Boinot C, et al. J Pharmacol Exp Ther. 2014 Sep;350(3):624-34.

2. Talebian L, et al. Cell Physiol Biochem. 2009;23(1-3):199-204.

3. Coffman KC, et al. J Med Chem. 2014 Aug 14;57(15):6729-38.

4. Pedemonte N, et al. Mol Pharmacol. 2005 Dec;68(6):1736-46.

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