Contezolid (MRX I)

Chemical Structure : Contezolid

CAS No.: 1112968-42-9

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货号: PC-61371Not For Human Use, Lab Use Only.

Contezolid (MRX I) is an orally active oxazolidinone agent with antibacterial activity Gram-positive pathogens, including MRSA, penicillin-PRSP, PISP, and vancomycin-resistant enterococci (VRE) with MIC of 0.25-4 ug/mL.

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10 mg	￥5880	In stock
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生物&药学活性

Contezolid (MRX I) is an orally active oxazolidinone agent with antibacterial activity Gram-positive pathogens, including MRSA, penicillin-PRSP, PISP, and vancomycin-resistant enterococci (VRE) with MIC of 0.25-4 ug/mL.
Contezolid demonstrates the same or better efficacy than linezolid in both systemic and local infection models against the tested strains.

物理化学性质&存储条件

分子量	408.337
分子式	C18H15F3N4O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-{2,3,6-trifluoro-4-[(5S)-5-{[(1,2-oxazol-3-yl)amino]methyl}-2-oxo-1,3-oxazolidin-3-yl]phenyl}-2,3-dihydropyridin-4(1H)-one

参考文献

1. Li CR, et al. Antimicrob Agents Chemother. 2014;58(4):2418-21.

2. Gordeev MF, et al. J Med Chem. 2014 Jun 12;57(11):4487-97.

3. Meng J, et al. Drug Metab Dispos. 2015 May;43(5):646-59.

4. Eckburg PB, et al. Antimicrob Agents Chemother. 2017 Mar 24;61(4). pii: e02181-16.

Contezolid (MRX I)

生物&药学活性

物理化学性质&存储条件

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Contezolid (MRX I)

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