Compound 797780-71-3

Chemical Structure : Compound 797780-71-3

加入收藏

货号: PC-22173Not For Human Use, Lab Use Only.

Compound 797780-71-3 is a small molevcule, covalent inhibitor of DJ-1 (PARK7), effectively inhibits the proliferation of ACHN cells with IC50 of 12.18 uM, inhibits the Wnt signaling pathway.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Compound 797780-71-3 is a small molevcule, covalent inhibitor of DJ-1 (PARK7), effectively inhibits the proliferation of ACHN cells with IC50 of 12.18 uM, inhibits the Wnt signaling pathway.
Compound 797780-71-3 demonstrates potent binding affinity in both noncovalent and covalent docking for DJ-1.
Compound 797780-71-3 (20 uM) completely inhibits the levels of β-catenin and the phosphorylation of GSK3β in ACHN cells.

物理化学性质&存储条件

分子量	301.73
分子式	C16H12ClNO3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2-(2-chlorophenoxy)ethyl)indoline-2,3-dione

参考文献

1. Yanyu Ma, et al. Future Med Chem. 2024 Apr;16(7):665-677.