Chemical Structure : Col003
CAS No.: 328565-16-8
货号: PC-62622Not For Human Use, Lab Use Only.
Col003 is a small-molecule compound that inhibits the interaction of Hsp47 with collagen with IC50 of 1.8 uM, binds to the collagen-binding site on Hsp47.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | ¥1180 | In stock | |
25 mg | ¥1880 | In stock | |
50 mg | ¥2980 | In stock | |
100 mg | Get quote |
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Col003 is a small-molecule compound that inhibits the interaction of Hsp47 with collagen with IC50 of 1.8 uM, binds to the collagen-binding site on Hsp47.
Col 003 competitively inhibits the interaction and causes the inhibition of collagen secretion by destabilizing the collagen triple helix.
分子量 | 257.245 | |
分子式 | C14H11NO4 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-benzyl-2-hydroxy-3-nitrobenzaldehyde |
1. Ito S, et al. J Biol Chem. 2017 Dec 8;292(49):20076-20085.
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