Chemical Structure : Codrituzumab
CAS No.: 1365267-33-9
货号: PC-Ab1037Not For Human Use, Lab Use Only.
Codrituzumab is a humanized monoclonal antibody targeted at glypican-3 (GPC3), which is a member of the glypican family. Codrituzumab binds to glypican-3 (GPC3). Glypican-3 (GPC3) is highly expressed in hepatocellular carcinoma (HCC). Codrituzumab triggers FcγRIIIa-mediated (CD16-mediated) antibody-dependent cell cytotoxicity (ADCC) and/or antibody-dependent cell phagocytosis..
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥3580 | In stock | |
5 mg | ¥7580 | In stock | |
10 mg | ¥12800 | In stock | |
100 mg | Get quote |
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Codrituzumab is a humanized monoclonal antibody targeted at glypican-3 (GPC3), which is a member of the glypican family. Codrituzumab binds to glypican-3 (GPC3). Glypican-3 (GPC3) is highly expressed in hepatocellular carcinoma (HCC). Codrituzumab triggers FcγRIIIa-mediated (CD16-mediated) antibody-dependent cell cytotoxicity (ADCC) and/or antibody-dependent cell phagocytosis.
分子量 | ||
分子式 | Human IgG1-Kappa | |
外观性状 | Solid | |
储存条件 |
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Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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Chemical Name/SMILES |
Codrituzumab; 1365267-33-9; GC33; RG 7686; RO 5137382; Glypican-3; GPC3 |
1. 1, Bell MM, et al. Molecules. 2020 Dec 22;26(1):4. 2, Guo T, et al. J Cancer. 2019 Aug 19;10(19):4671-4678. 3, Onyeisi JOS, et al. Cancer Biol Ther. 2020 Dec 1;21(12):1087-1094. 4, Nakamura M, et al. Br J Clin Pharmacol. 2018 May;84(5):944-951.
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