ClpP inhibitor M21 |CAS:1151944-58-9 Probechem Biochemicals

Chemical Structure : ClpP inhibitor M21

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ClpP inhibitor M21

货号: PC-35421Not For Human Use, Lab Use Only.

ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay.

规格	价格	库存	数量
100 mg		Get quote
250 mg		Get quote
500 mg		Get quote
1 g		Get quote

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生物&药学活性

ClpP inhibitor M21 is a noncompetitive inhibitor of ClpP with IC50 of 41.42 uM, inhibits ClpP cleavage of SUc-LY-AMC substrate in a peptidase assay.
ClpP inhibitor M21 alters α-toxin expression in a ClpP-dependent manner and attenuate S. aureus virulence via ClpP inhibition.
ClpP inhibitor M21 blocks the pathogenicity of infection in animal models.

物理化学性质&存储条件

分子量	385.452
分子式	C19H15NO4S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(Z)-2-(5-(4-(benzyloxy)benzylidene)-4-oxo-2-thioxothiazolidin-3-yl)acetic acid

参考文献

1. Gao P, et al. Proc Natl Acad Sci U S A. 2018 Jul 16. pii: 201720520.