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首页-小分子抑制剂&激动剂-Cell Cycle/DNA Damage-DNA Alkylator/Crosslinker-Cisplatin
Cisplatin

Chemical Structure : Cisplatin

CAS No.: 15663-27-1

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Cisplatin (CDDP, cis-Diaminodichloroplatinum)

货号: PC-45216Not For Human Use, Lab Use Only.

Cisplatin is a chemotherapy agent that interferes with DNA replication and kills cancer cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cisplatin is a chemotherapy agent that interferes with DNA replication and kills cancer cells.
Cisplatin induces growth arrest and/or apoptosis in most cancer cell types.
Cisplatin is an alkylating agent for treatment of a number of cancers.

物理化学性质&存储条件

分子量 300.051
分子式 Cl2H6N2Pt
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

DMSO: ≥ 31 mg/mL (DMSO can inactivate Cisplatin's activity; please see the reference [5]).
Chemical Name/SMILES

Platinum, diamminedichloro-, (SP-4-2)-

参考文献

1. Wang X, et al. J Biol Chem. 2000 Dec 15;275(50):39435-43.

2. Cummings BS, et al. J Pharmacol Exp Ther. 2002 Jul;302(1):8-17.

3. Hall MD, et al. Cancer Res. 2014 Jul 15;74(14):3913-22.

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