Ciliogenesis inhibitor Nao-3 | Ciliogenesis inhibitor

Chemical Structure : Ciliogenesis inhibitor Nao-3

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Ciliogenesis inhibitor Nao-3 (Naonedin-3)

货号: PC-25807Not For Human Use, Lab Use Only.

Ciliogenesis inhibitor Nao-3 (Naonedin-3) is specific small-molecule inhibitor of ciliogenesis, represses primary ciliogenesis and induces the death of chemoresistant ciliated stem-like cells.

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生物&药学活性

Ciliogenesis inhibitor Nao-3 (Naonedin-3) is specific small-molecule inhibitor of ciliogenesis, represses primary ciliogenesis and induces the death of chemoresistant ciliated stem-like cells.
Nao-3 significantly represses cilium assembly in multiple patient samples in a dose-dependent manner（IC50=47.1 nM）

物理化学性质&存储条件

分子量	409.87
分子式	C23H20ClNO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(6-chloro-1,4-dimethyl-9H-carbazol-3-yl)(4-hydroxy-3,5-dimethoxyphenyl)methanone

参考文献

1. Tessier CE, et al. EMBO Mol Med. 2025 Oct;17(10):2536-2561.

Ciliogenesis inhibitor Nao-3 (Naonedin-3)

生物&药学活性

物理化学性质&存储条件

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Ciliogenesis inhibitor Nao-3 (Naonedin-3)

生物&药学活性

物理化学性质&存储条件

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