Chloroquine

Chemical Structure : Chloroquine

CAS No.: 54-05-7

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货号: PC-24786Not For Human Use, Lab Use Only.

Chloroquine is an antimalarial drug and autophagy/lysosome inhibitor, inhibiting Toll-like receptor (TLR) signalling.

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50 mg	￥280	In stock
100 mg	￥380	In stock
250 mg	￥580	In stock
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生物&药学活性

Chloroquine is an antimalarial drug and autophagy/lysosome inhibitor, inhibiting Toll-like receptor (TLR) signalling.
Chloroquine inhibits IL-12p70 release and reduces Th1-priming capacity of activated human monocyte-derived Langerhans-like cells (MoLC) at 20 uM.
Chloroquine significantly reduces HuH7 cell proliferation in vitro and inhibited tumour growth in the mouse xenograft model.

物理化学性质&存储条件

分子量	319.88
分子式	C18H26ClN3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N4-(7-Chloroquinolin-4-yl)-N1,N1-diethylpentane-1,4-diamine

参考文献

1. Said A, et al. J Immunol. 2014 Dec 15;193(12):6135-43.

2. Tuomela J, et al. Oncol Lett. 2013 Dec;6(6):1665-1672.

3. Mohamed FE, et al. Liver Int. 2015 Mar;35(3):1063-76.

Chloroquine

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Chloroquine

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