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Cetrimonium bromide

Chemical Structure : Cetrimonium bromide

CAS No.: 57-09-0

Cetrimonium bromide (CetB)

货号: PC-26826Not For Human Use, Lab Use Only.

Cetrimonium bromide (CetB) is a specific small-molecule inhibitor of Epstein-Barr virus (EBV) latently infected cancer cells, reduces EBNA1 protein stability, activates G1 arrest and early apoptosis of EBV-latently infected cells without viral lytic reactivation, modulates canonical and non-canonical TGF-β signaling pathways, inhibits cancer cell migration and invasion.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cetrimonium bromide (CetB) is a specific small-molecule inhibitor of Epstein-Barr virus (EBV) latently infected cancer cells, reduces EBNA1 protein stability, activates G1 arrest and early apoptosis of EBV-latently infected cells without viral lytic reactivation, modulates canonical and non-canonical TGF-β signaling pathways, inhibits cancer cell migration and invasion.

物理化学性质&存储条件

分子量 364.46
分子式 C19H42BrN
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N,N,N-Trimethylhexadecan-1-aminium bromide

参考文献

1. Li Y, et al. iScience. 2024 Jul 25;27(9):110581.

2. Wu T K, et al. Anticancer Research, 2019, 39(7): 3621-3631.

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