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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-Bacterial-Cerastecin B
Cerastecin B

Chemical Structure : Cerastecin B

CAS No.: 3014434-63-7

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Cerastecin B

货号: PC-22208Not For Human Use, Lab Use Only.

Cerastecin B is a potent small molecule inhibitor of A. baumannii transporter MsbA with binding KD of 0.37 nM, is a potent and bactericidal against A. baumannii, including clinical carbapenem-resistant Acinetobacter baumannii isolates.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Cerastecin B is a potent small molecule inhibitor of A. baumannii transporter MsbA with binding KD of 0.37 nM, is a potent and bactericidal against A. baumannii, including clinical carbapenem-resistant Acinetobacter baumannii isolates.

物理化学性质&存储条件

分子量 778.89
分子式 C38H42N4O10S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

5,5'-(succinylbis(azanediyl))bis(2-((4-butylphenyl)sulfonamido)benzoic acid)

参考文献

1. Hao Wang, et al. Nat Microbiol. 2024 Apr 22. doi: 10.1038/s41564-024-01667-0.

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