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首页-小分子抑制剂&激动剂-Nuclear Receptor/Transcription Factor-ROR-Cedirogant
Cedirogant

Chemical Structure : Cedirogant

CAS No.: 2055496-11-0

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Cedirogant (ABBV-157, ABBV157)

货号: PC-38349Not For Human Use, Lab Use Only.

ABBV-157 (Cedirogant) is a small molecule inhibitor (inverse agonist) of RORγT being investigated for the treatment of immune-mediated diseases (e.g. Psoriasis).

规格 价格 库存 数量
5 mg ￥1580 In stock
10 mg ￥2380 In stock
25 mg ￥3980 In stock
50 mg ￥5980 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

ABBV-157 (Cedirogant) is an orally bioavailable small molecule inhibitor (inverse agonist) of RORγT being investigated for the treatment of immune-mediated diseases (e.g. Psoriasis).

物理化学性质&存储条件

分子量 547.780
分子式 C24H20Cl3F3N2O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

2-(1-(2,4-dichloro-3-((7-chloro-5-(trifluoromethyl)-1H-indol-1-yl)methyl)benzoyl)piperidin-4-yl)acetic acid

参考文献

1. Christian Gege. Expert Opin Drug Discov. 2021 Dec;16(12):1517-1535.

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