Cecropin B |CAS:80451-05-4 Probechem Biochemicals

Chemical Structure : Cecropin B

CAS No.: 80451-05-4

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Cecropin B

货号: PC-47495Not For Human Use, Lab Use Only.

Cecropin B is an antimicrobial peptide with MICs (0.5 to 16 ug/ml) against Gram negative strain, also inhibit the expression of CYP3A29.

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1 mg	￥1180	In stock
5 mg	￥2880	In stock
10 mg	￥4580	In stock
25 mg		Get quote

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生物&药学活性

Cecropin B is an antimicrobial peptide with MICs (0.5 to 16 ug/ml) against Gram negative strain, also inhibit the expression of CYP3A29.
Cecropin B induces NF-κB activation playing a pivotal role in the suppression of CYP3A29 through disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA sequences.
Cecropin B activates pig liver cells by interacting with TLRs 2 and 4, which modulated NF-κB-mediated signaling pathways

物理化学性质&存储条件

分子量	3834.67
分子式	C176H302N52O41S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	H2O: 10 mM (38.3 mg/mL)
Chemical Name/SMILES	L-Leucinamide, L-lysyl-L-tryptophyl-L-lysyl-L-valyl-L-phenylalanyl-L-lysyl-L-lysyl-L-isoleucyl-L-α-glutamyl-L-lysyl-L-methionylglycyl-L-arginyl-L-asparaginyl-L-isoleucyl-L-arginyl-L-asparaginylglycyl-L-isoleucyl-L-valyl-L-lysyl-L-alanylglycyl-L-prolyl-L-a

参考文献

1. Hu H, et al. Mol Cells. 2013 Feb;35(2):106-14.

2. Zhou X, et al. Sci Rep. 2016 Jun 14;6:27876.

3. Chen F, et al. J Mol Microbiol Biotechnol. 2015;25(4):284-91.

Cecropin B

生物&药学活性

物理化学性质&存储条件

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Cecropin B

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