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CeMMEC2

Chemical Structure : CeMMEC2

CAS No.: 902955-25-3

CeMMEC2 (CeMMEC 2)

货号: PC-62288Not For Human Use, Lab Use Only.

CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    CeMMEC2 is a novel potent BRD4 inhibitor with IC50 of 0.9 uM, binds to both bromodomains of BRD4, comparably to (S)-JQ1.

    物理化学性质&存储条件

    分子量 257.34
    分子式 C14H19N5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-[2-(cyclohex-1-en-1-yl)ethyl]-3-methyl[1,2,4]triazolo[4,3-b]pyridazin-6-amine

    参考文献

    1. Sdelci S, et al. Nat Chem Biol. 2016 Jul;12(7):504-10.

    2. Blank, J. et al. WPO patent WO/2014/191894 (2014).

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