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首页-小分子抑制剂&激动剂-Epigenetics-Bromodomain-CeMMEC13
CeMMEC13

Chemical Structure : CeMMEC13

CAS No.: 1790895-25-8

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CeMMEC13 (CeMMEC 13)

货号: PC-62290Not For Human Use, Lab Use Only.

CeMMEC13 is a selective TAF1 second bromodomain (TAF1 (2)) inhibitor with IC50 of 2.1 uM.

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10 mg ￥1280 In stock
25 mg ￥2180 In stock
50 mg ￥3680 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

CeMMEC13 is a selective TAF1 second bromodomain (TAF1 (2)) inhibitor with IC50 of 2.1 uM.
CeMMEC13 shows high selectivity for the TAF1 (2) bromodomain over BRD4 (1), BRD9, CREBBP, EP300 and TAF1 (2) bromodomains (IC50>10 uM).
CeMMEC13 synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.

物理化学性质&存储条件

分子量 336.3
分子式 C19H16N2O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(2,3-dihydro-1,4-benzodioxin-6-yl)-1,2-dihydro-1-methyl-2-oxo-4-quinolinecarboxamide

参考文献

1. Sdelci S, et al. Nat Chem Biol. 2016 Jul;12(7):504-10.

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