Cbl-b inhibitor 33

Chemical Structure : Cbl-b inhibitor 33

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货号: PC-27095Not For Human Use, Lab Use Only.

Cbl-b inhibitor 33 is a potent, selective, inactive-state inhibitor of E3 ligase Casitas B-lineage lymphoma proto oncogene B (Cbl-b) with SPR Kd of 2.4 nM, has 14-fold selectivity over c-Cbl.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote

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Cbl-b inhibitor 33 is a potent, selective, inactive-state inhibitor of E3 ligase Casitas B-lineage lymphoma proto oncogene B (Cbl-b) with SPR Kd of 2.4 nM, has 14-fold selectivity over c-Cbl.

物理化学性质&存储条件

分子量	539.60
分子式	C29H32F3N5O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-((1r,3r)-3-methoxy-1-(4-methyl-4H-1,2,4-triazol-3-yl)cyclobutyl)phenyl)-6-(((1-methylcyclobutyl)amino)methyl)-4-(trifluoromethyl)isoindolin-1-one

参考文献

1. Liang J, et al. ACS Med Chem Lett. 2026 May 27;17(6):1258-1265.