Cas9 inhibitor 85 |CAS 2866499-55-8 Probechem Biochemicals

Chemical Structure : Cas9 inhibitor 85

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Cas9 inhibitor 85

货号: PC-38224Not For Human Use, Lab Use Only.

Cas9 inhibitor 85 is a small-molecule ligand with anti-CRISPR/Cas9 activity with IC50 of 7 uM, binds to Apo-Cas9 and inhibits Cas9:gRNA complex formation.

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50 mg		Get quote
100 mg		Get quote

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生物&药学活性

Cas9 inhibitor 85 is a small-molecule ligand with anti-CRISPR/Cas9 activity with IC50 of 7 uM, binds to Apo-Cas9 and inhibits Cas9:gRNA complex formation.

物理化学性质&存储条件

分子量	451.241
分子式	C17H11Cl2F3N2O3S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3′,4′-Dichloro-N-(5-methyl-3-isoxazolyl)-5-(trifluoromethyl)[1,1′-biphenyl]-3-sulfonamide

参考文献

1. Sang-Woo Lee, et al. J. Med. Chem. 2022; 65(4), 3266-3305.