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Cariprazine

Chemical Structure : Cariprazine

CAS No.: 839712-12-8

Cariprazine (RGH-188, RGH188)

货号: PC-24329Not For Human Use, Lab Use Only.

Cariprazine (RGH-188) is an antipsychotic compound that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Cariprazine (RGH-188) is an antipsychotic compound that exhibits high affinity for the D3 (Ki=0.085 nM) and D2 (Ki=0.49 nM) receptors, and moderate affinity for the 5-HT1A receptor (Ki=2.6 nM).

物理化学性质&存储条件

分子量 427.41
分子式 C21H32Cl2N4O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-(trans-4-(2-(4-(2,3-Dichlorophenyl)piperazin-1-yl)ethyl)cyclohexyl)-1,1-dimethylurea

参考文献

1. Seneca N, et al. Psychopharmacology (Berl). 2011 Dec;218(3):579-8

2. Kiss B, et al. J Pharmacol Exp Ther. 2010 Apr;333(1):328-40.

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