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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-11β-HSD-Carbenoxolone
Carbenoxolone

Chemical Structure : Carbenoxolone

CAS No.: 5697-56-3

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Carbenoxolone (YP 003)

货号: PC-60344Not For Human Use, Lab Use Only.

Carbenoxolone is a glycyrrhetinic acid derivative that inhibits 11β-hydroxysteroid dehydrogenase (11β-HSD), a gap junction blocker and mineralocorticoid agonist.

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100 mg ￥980 In stock
200 mg ￥1580 In stock
500 mg ￥2980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Carbenoxolone is a glycyrrhetinic acid derivative that inhibits 11β-hydroxysteroid dehydrogenase (11β-HSD), a gap junction blocker and mineralocorticoid agonist.

物理化学性质&存储条件

分子量 570.765
分子式 C34H50O7
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid

参考文献

1. Sagar GD, et al. J Cell Biochem. 2006 Aug 15;98(6):1543-51.

2. Hanukoglu A, et al. J Steroid Biochem Mol Biol. 1997 Jan;60(1-2):105-12.

3. Lindsay RS, et al. Hypertension. 1996 Jun;27(6):1200-4.

4. Ross FM, et al. Neuroscience. 2000;100(4):789-96.

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